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Biomedical subjects

A A Tret'iakov

Publications and source records attributed to A A Tret'iakov.

At least 19 recordsLinked to original sources

[Taxonomic spectrum and antibiotic resistance of Enterobacteriaceae isolated from bile of patients with cholangitis].

The data on the taxonomic structure and antibiotic resistance of Enterobacteriaceae isolated from bile of patients with various clinical variants of cholangitis are presented. It was shown that bacteriocholia was registered in 53.3-90.9% of the patients during operations and in 88.9-100% of the patients during the postoperative period. Among bilicultures enterobacteria dominated (93.4% of the cases) with predominance of E. coli and Klebsiella spp. (the total about 70%). The enterobacteria isolates were frequently resistant to ampicillin and amoxycillin/clavulanate (92.6 and 70.4% of the strains respectively), gentamicin and amikacin (74.1 and 22.2%), cefazolin and cefotaxime (88.9 and 37.0%). The resistance to imipenem and ciprofloxacin (7.4%) was rare, that should be considered while prescribing drugs for empirical antimicrobial chemotherapy.

Adult↗

[Effectiveness of sporobacterin in the prevention and treatment (of postoperative wound infections)].

Peculiarities of penetration of living bacterial cultures of Bacillus strain into the structures of the abdominal wall, their positive influence upon the reparative regeneration of surgical wounds were studied in experiments in 240 rats. It was found the living bacterial preparation to be expedient to use as an antagonist of pyogenic infection for purulent postoperative wounds and in order to prevent its development. The clinical antiinflammatory and stimulating the reparative process effects of sporobacterin were studied in 50 patients with infectious wound complications after urgent and scheduled operations. A prophylactic effect was noted in 145 patients operated on for complications of cholelithiasis and commissural ileus. Sporobacterin was proved to give better results of treatment as compared with traditional methods of antiinflammatory therapy with antibiotics.

Adolescent↗

[Pathogenetic mechanisms of bacterial cholangitis in mechanical jaundice (experimental histological study)].

In 89 rats with experimentally induced mechanical jaundice the infectious process was modeled by intragastric administration of E. coli and B. subtilis. The study included the investigation of the main routes and time intervals of dissemination, organ content of microbes labeled with 3H-thymidine, as well as of structural and functional peculiarities of the interaction of animal tissues with the microbes in cholestasis development dynamics and under the condition of biliary tract decompression. It was established that under the condition of mechanical jaundice viable bacteria from the alimentary tract penetrated the organs of peritoneal cavity through the blood and lymph flow. In the liver, the endogenous agents of surgical infections, and E. coli, in particular, were found to aggravate the inflammatory and necrobiotic processes. B. subtilis did not cause any inflammatory or other pathologic process in the tissue of liver.

Animals↗

[The morphological characteristics of microsurgical biliodigestive anastomoses].

The morphological characteristics of 3 new types of microsurgical biliodigestive antireflux anastomosis created in 66 mongrel dogs has been presented. Histotopographic data in all series of experiment are indicative of the accretion of mucous coats of sutured organs not later than on d 4-6. The regeneration processes in wound channel finishes on d 14 without forming of a scar. Adaptation mechanisms, occurring in the area of biliodigestive junctions are manifested through dislocation of the intestinal mucosa into the biliary duct, the change of its surface and hypertrophy of the intestinal circular muscles, surrounding the anastomosis, which provides its antireflux characteristic.

Anastomosis, Surgical↗

[Surgical treatment of intraoperative injuries and cicatricial strictures of extrahepatic bile ducts].

The analysis of 70 cases of surgical treatment for intraoperative injuries and cicatricial strictures of extrahepatic bile ducts was carried out. In 25 patients surgical procedure was restorative and in 45--reconstructiver. Most common causes of corrective operations were: iatrogenic injuries of extrahepatic bile ducts (14) and cicatricial strictures of hepaticocholedochal duct due to intraoperative trauma (31). The problems of operative technique in performing biliobilio-, hepato-hepatico and hepatico-jejuno-anastomoses are considered. There were three deaths in the early postoperative period: 2 patients died of hepatic failure, pyogenic cholangiogenic intoxication caused by cholangioectasies and intrahepatic abscesses, and 1-due to generalyzed peritonitis caused by acute gastric ulcer perforation. Special attention is paid to the choice of the method of prolonged drainage used in reconstructive as well as in restorative operations.

Anastomosis, Surgical↗

[The experimental morphological bases for using a microsurgical technic and demineralized bone in the restorative surgery of hollow organs and blood vessels].

By means of experimental material from 339 animals it was shown that microsurgical technique provides primary recovery of the wounds of the hollow organs, their anastomoses and blood vessels: demineralized bone is found to be a suitable material easily adapting in implantation. The use of microsurgical methods and technique and demineralized osseus matrix for nonosseous plastics is a perspective direction in improvement of the results of reconstructive and restorative operations on hollow organ and blood vessels.

Abdomen↗

[Disorders of motor function of the stomach in acute appendicitis].

The authors have studied the motoric activity of the stomach in 40 patients with acute appendicitis and in 15 patients with other lesions. In appendicitis the strength and depth of gastric contractions were found to be mostly labile, while the number of waves of gastric contractions was relatively constant.

Acute Disease↗

[Surgical treatment of suppurative hydatid echinococcosis of the liver].

Among 140 patients with hydatid echinococcosis of the liver complications were noted in 58 cases: suppuration of the cyst - in 38 (27.1%), cyst rupture in the anterior abdominal wall and abdominal cavity - in 4 (2.8%), in bile ducts - in 10 (7.1%), its rupture into the right lung lower lobe, calcification of the cyst was noted in 4 patients (2.8%). It is concluded that open echinococcotomy with partial excision of the fibrous capsule and drainage of the residual cavity with a rubber tube seem to be the most effective operation for suppurative echinococcosis of the liver.

Adolescent↗