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Biomedical subjects

A A Rosenbloom

Publications and source records attributed to A A Rosenbloom.

At least 19 recordsLinked to original sources
PubMed1991

Low vision ahead.

Explore the source record for details and available documents.

Forecasting↗
PubMed1991

Geriatric optometry questionnaire.

A national survey of American Optometric Association Low Vision Section members was conducted by the newly formed Geriatrics and Low Vision Committee during the fall of 1989. The "Geriatric Optometry Questionnaire" was designed to establish a greater understanding of the nature of comprehensive professional services for the unique needs of visually impaired older persons. Of the 481 surveys mailed, 289 were returned for a response rate of 60 percent. Seventy-eight percent of the respondents had completed their formal optometric education after 1970. Results indicated that geriatric optometric care is predominantly delivered in private practices and in low vision agencies. Approximately 69 percent of the patients are above the age of 65, with the majority of those being under 85. Although the average initial low vision appointment lasts 60-90 minutes, this generally represents the low vision examination and evaluation of low vision devices only. Complete ocular health assessments combined with low vision evaluations are provided by only 33.5 percent. While 80 percent of the optometrists responding take psychosocial histories, only 60 percent routinely refer patients for social services and rehabilitative training. Similarly, 57 percent of those responding referred patients for independent daily living skills instruction and only 53 percent for orientation and mobility training. These data suggest that optometrists have not yet completely incorporated the multidisciplinary approach to geriatric health care and that continuing education in this area is needed.

Aged↗
PubMed1988

Essential factors in the care of elderly patients.

With the increase in life expectancy since the turn of the century, all optometrists must have a good understanding of essential factors in the care of elderly patients. Some of the most important aspects of the clinical approach to and understanding of the elderly patient are considered here. Characteristic differences in symptomatology, the altered doctor-patient relationship, polypharmacy and compliance issues, and altered environmental needs are also described.

Aged↗
PubMed1978

Pituitary adenomas associated with elevated blood follicle-stimulating hormone levels: a histologic, immunocytologic, and electron microscopic study of two cases.

The histologic, immunocytologic, and electron microscopic features of pituitary adenomas surgically removed from two men with elevated levels of blood follicle-stimulating hormone (FSH) are described. In both cases, the high blood FSH levels were reduced after surgery. By light microscopy, the tumors corresponded to chromophobic adenomas, and the immunoperoxidase technique revealed the presence of immunoreactive FSH (beta-subunit) in the cytoplasm of the adenoma cells. By electron microscopy, the adenoma cells differed considerably from nontumorous FSH cells. They were smaller and angular and contained numerous microtubules as well as spherical secretory granules measuring 100 to 250 nm in diameter and often lining up along the cell membranes. The present findings are consistent with the view that FSH-producing adenomas may originate in the human pituitary.

Adenoma↗
PubMed1978

Research needs in low vision.

Research needs are presented for several areas of low vision: (1) reading and learning, (2) new low-vision aids, (3) modifying the environment, (4) utilization of disciplines, (5) new technologies, and (6) integrating low-vision services.

Audiovisual Aids↗
PubMed1977

Case reports and studies of paraneoplastic hypotension: abnormal low pressure baroreceptor responses.

Intrathoracic stretch receptors regulate adjustments of the vasculature to gravitational changes and influence urinary water and solute excretion. Few reports of pathologic states involving interruption of these regulatory mechanisms have appeared. Two patients with orthostatic hypotenstion related to advanced intrathoracic carcinoma were studied, utilizing tilt-table examinations and immersion of the entire body in water to test the function of their intrathoracic baroreceptor reflex arcs. Both patients showed abnormalities of antidiuretic hormone level and sodium excretion as compared with normal controls. This suggests that total immersion is a safe and convenient test of the low-pressure baroreceptor system in patients with suspected dysfunction. Three patients are also reported whose charts were reviewed posthumously. Although they were not tested in the laboratory, their clinical data suggest that they too had been suffering from an interference with the transmission of impulses from the intrathoracic receptors.

Adult↗
PubMed1977

Leadership and change in optometric education.

The quality of institutional administration and the competence of its academic leaders are considered to be crucial elements in the continued progress of optometric education. Educational leadership to meet the need for ongoing, guided, systematic educational planning is underscored. Such planning, in turn, depends significantly on the emerging role definition of the optometrist as a primary care practitioner.

Education↗
PubMed1975

The circulating vasopressinase of pregnancy: species comparison with radioimmunoassay.

A vasopressin substrate radioimmunoassay (RIA) system is described for the measurement of the vasopressinase elaborated during pregnancy. Results show that vasopressinase activity increases in the sera of pregnant women throughout gestation. At term, under the in vitro conditions described, pregnancy serum degrades vasopressin (Pitressin) at a rate of 53 mU. per milliliter of serum per minute. Serum obtained from paired umbilical cord samples had an activity of 9.2 muU per milliliter per minute; amniotic fluid obtained at delivery had an activity of 16.6 muU per milliliter per minute. Pregnancy serum obtained from sheep, rabbits, and rats, ovine umbilical cord serum, and ovine amniotic fluid had no detectable vasopressinase activity. Normal human male serum, nonpregnant female serum, and serum from women taking contraceptive agents also exhibited no activity.

Aminopeptidases↗
PubMed1975

Prostatic carcinoma producing syndrome of inappropriate secretion of antidiuretic hormone.

The syndrome of inappropriate secretion of antidiuretic hormone was recognized in a sixty-year-old man with a poorly differentiated metastatic adenocarcinoma of the prostate gland. Elevated levels of antidiuretic hormone were found in the patient's serum and in the prostatic tumor but not in the cerebrospinal fluid. The patient's clinical course is detailed, and the pathophysiology of this syndrome is discussed.

Adenocarcinoma↗
PubMed1975

Radioimmunoassayable avt and avp in adult mammalian brain tissue: comparison of normal and brattleboro rats.

Arginine vasopressin (AVP) and vasotocin (AVT) were measured by radioimmunoassay in extracts of cerebral cortex, cerebellum, brain stem, pineal, hypothalamus, and neurohypophysis from normal Long-Evans rats. AVP was present in expected concentrations in pituitary and hypothalamus and there was no evidence of its accumulation elsewhere. AVT was not detectable in these tissues (within the limits imposed on our assay by the presence of excessive amounts of AVP) but was easily detectable in pineal tissue with a concentration of 22.4 plus or minus 6.6 muU/gland. Extracts of neurohypophysis and pineal glands from homozygous Brattleboro rats (rats with hereditary hypothalamic diabetes insipidus) revealed the total absence of AVP and AVT. We conclude that the Brattleboro rat is incapabel of synthesizing biologically active neurohypophyseal peptides which contain arginine in position 8.

Animals↗
PubMed1975

Arginine vasotocin in the rabbit subcommissural organ.

Subcommissural organs of young and mature rabbits were analyzed for their content of arginine vasotocin by radioimmunoassay. Younger animals had significantly greater quantities of this peptide. There was no detectable arginine vasopressin or oxytocin in subcommissural organ extracts. It is concluded that the subcommissural organ represents, in addition to the pineal and the fetal neurohypophysis, another significant source of arginine vasotocin in the mammalian central nervous system.

Age Factors↗