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Biomedical subjects

A A Obuoforibo

Publications and source records attributed to A A Obuoforibo.

6 recordsLinked to original sources
PubMed1987

The use of footprint contact index II for classification of flat feet in a Nigerian population.

The objective index as developed by Qaura, Deodhar, and Jit, in 1980 was used to estimate the incidence of flat foot (pes planus) in 990 school pupils (532 females and 458 males) between the ages of 5 and 14 years. The ratio of contact area to the total area of the middle of the footprint (contact index 1) (4/10), usually measured with a planimeter, is accepted as the true representative of the condition of arches. In this field study, contact index II (ratio of contact width to the total width of the foot) which is simple, reliable, and correlates with contact index I has been used to assess flat foot. The mean for the contact index and standard deviation have been calculated. Feet have been considered as normal up to 1 SD around the mean value of the index and values greater or lesser than this have been considered abnormal. Furthermore, mean +/- 1 SD to 2 SD has been considered as possible flat foot, whereas mean +/- 3 SD and above has been taken as definite flat foot. On the whole, bilateral flat foot is not common among children of school age in Port Harcourt (0.60%). It is, however, more common in females (0.75%) than males (0.44%). Unilateral flat foot (2.22%) is found to be more common than bilateral flat foot. Early introduction to the use of shoes may predispose to flat foot. We were not in a position to say if any of the subjects found with flat foot would have a painful foot.(ABSTRACT TRUNCATED AT 250 WORDS)

Child↗
PubMed1977

Postnatal growth of Brunner's glands in the mouse.

In the newborn mouse the glands of Brunner consist of a few tubular downgrowths from the proximal duodenal crypts. Within three weeks the characteristic 'comma' shape of the gland is established by later downgrowths from more distal growths. The gland cells, although specialized from birth, show a high mitotic index, and a high labelling index with 3H-T, during the first three weeks, and particularly during the first two weeks. Nevertheless, the daily mitotic rate during this period is insufficient to account for the daily addition of glandular cells, suggesting that there is a continuing contribution of cells from the crypts. After this time, however, the mitotic activity of the mature gland cells is sufficient to account for the continuing increase in cell population. After the fourth postnatal week the mitotic and labelling indices decline markedly, and although mitoses are rarely seen in individual sections from older animals, cellular addition at a very slow rate is sufficient to account for the gradual expansion in size of the gland, and the process continues long after the adult body weight has been established.

Animals↗
PubMed1975

Mucosubstances in Brunner's glands of the mouse.

The mucins of Brunner's glands in the mouse have been studied by histochemical methods. The secretion droplets in both acinar cells and the cells lining the ducts are PAS-positive and diazyme-resistant. The latter cells are alcianophilic at pH 2.5, react positively with Hale's colloidal iron method and exhibit metachromasia with azure A. The reaction to Hale's colloidal iron method is lost after digestion with neuraminidase. These results suggest that an acid as well as a neutral mucopolysaccharide is present in the secretion of Brunner's glands of the mouse, the acid mucosubstance being a sialomucin. The possible significance of this finding is discussed. This work was performed in partial fulfilment of work for the degree of Doctor of Philosophy of the University of Sheffield. It was supported by a Research Fellowship from the World Health Organisation (W.H.O.) during a study leave granted by the University of Lagos, Nigeria.

Animals↗