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Biomedical subjects

A A Majid

Publications and source records attributed to A A Majid.

At least 19 recordsLinked to original sources

Thymolipoma.

Although the diagnosis of thymolipoma has improved with the introduction of computerized tomography (CT), variations in CT appearance are still being described; this paper describes a case which resembled a lipoma. The CT features of thymolipoma are discussed with special reference to the differential diagnosis. Surgical excision should be considered for patients who are found to exhibit a fatty intrathoracic mass on CT.

Adult↗

Pain control after thoracotomy. An extrapleural tunnel to provide a continuous bupivacaine infusion for intercostal nerve blockade.

This study was undertaken to determine whether an infusion of local anesthetic (LA) delivered through an extrapleural tunnel could provide satisfactory control of pain in the postthoracotomy period. Twelve patients undergoing thoracotomy were studied. A T-shaped tunnel was created by elevating the parietal pleura at the posteromedial end of the thoracotomy wound. An irrigation catheter was then inserted and an infusion of bupivacaine commenced, initially at 5 mg/kg/24 h and subsequently at 3 mg/kg/24 h. Pain was well controlled in eight patients and satisfactory in four patients. The latter required one dose of opiate analgesia each in the 48-h postoperative period. We conclude that an infusion of bupivacaine into the extrapleural space is an effective means of control of pain after thoracotomy.

Adult↗

Granulomatous pulmonary zygomycosis in a patient without underlying illness. Computed tomographic appearances and treatment by pneumonectomy.

Pulmonary zygomycosis rarely occurs in the absence of underlying disease. We report a patient with granulomatous pulmonary zygomycosis without underlying disease who presented with a pulmonary mass. We present the computed tomographic findings that we believe have not been described previously. We also report the successful treatment by pneumonectomy.

Aged↗

Diagnosis and management of purulent pericarditis. Experience with pericardiectomy.

Twelve cases of purulent pericarditis seen over 6 years are described. Staphylococcus aureus was the most common causative organism (six patients), and a respiratory infection was the most common preceding illness. The chest radiograph and echocardiogram were useful pointers to the diagnosis, but the electrocardiogram was not reliable. Antibiotics, surgical drainage, and pericardiectomy were used in all 12 cases. There was one death (8.3%), which occurred in a patient who was seen late. A review of the literature dealing with the diagnosis and management of this condition is presented. The importance of early diagnosis before a significant degree of cardiac tamponade occurs is noted. Although there is general agreement that surgical drainage is mandatory, the approach, methods of drainage, and extent of pericardial resection have been the subject of some discussion, and at least seven techniques are available. We conclude that pericardiectomy has a definite place in the management of purulent pericarditis.

Adult↗

Fractured silver tracheostomy tube: a case report and literature review.

This report raises the question of the long term durability of tracheostomy tubes and describes a patient who inhaled part of a silver tracheostomy tube after it fractured. A review of the literature is presented, which compares the clinical presentations and methods of management described in previous reports. From this review frequent sites of tracheostomy tube fracture have been identified and a method of improvement in manufacture is suggested.

Bronchi↗

Clinical diagnosis of schistosomiasis in Sudanese cattle.

This study was done in the White Nile Province to characterise the history and signs of naturally occurring Schistosoma bovis infection in cattle (Gorag). Necropsy and laboratory examinations were performed on 10 animals six to 30 months of age which were in poor condition. They were selected because of a history suggestive of schistosomiasis. All the animals showed some degree of S. bovis infection; eight had a moderate or heavy degree of infection. Also all had liver damage due to either past or active Fasciola gigantica infection. Although concurrent infection with these two trematodes is common an owner who diagnoses Gorag is most likely referring to the syndrome caused by S. bovis as being the major cause of the poor performance observed. Fasciolicide treatment may eliminate active fascioliasis as the principal damaging agent. Also differentiating signs of haemorrhagic diarrhoea, severely sunken eyed appearance and only moderate inappetence are common in animals with acute schistosomiasis.

Animals↗

Owner survey of schistosomiasis mortality in Sudanese cattle.

The estimated mortality in six- to 30-month-old cattle due to presumptive schistosomiasis was 7.1% for 155 interviews conducted in the White Nile Province in 1981. This mortality was higher for those herds under sedentary management than for migratory herds (9.4% vs 3.6%). The interviews were done through an informal visit technique by a veterinarian living in the area. The approximate number (19,000) of cattle over six months old estimated to be owned by those interviewed represents about 1% of the population in that province. The mortality from all causes in the six- to 30-month age group was 9.2%; in the over 30-month age group it was 1.8%. The authors judge the schistosomiasis mortality to be somewhat upwardly biased but the mortality due to all causes (9.2%) is consistent with the few reports available.

Age Factors↗

Observations on cattle schistosomiasis in the Sudan, a study in comparative medicine. V. The effect of praziquantel therapy on naturally acquired resistance to Schistosoma bovis.

Studies in the White Nile area of the Sudan have shown that Zebu cattle acquire a high degree of resistance to Schistosoma bovis as a result of repeated natural exposures without, however, being able to eliminate their populations of adult schistosomes, although these do show greatly suppressed fecundity. To test whether these adult worms are necessary for the maintenance of resistance we cured six "naturally resistant" cattle (TC group) with a double treatment of 25 mg/kg praziquantel and compared their response to a 70,000 cercariae challenge with groups of "naturally resistant" but untreated cattle (UC group) and with previously unexposed, challenged cattle (CC group). Challenge was carried out 7 weeks after the second dose of praziquantel. The results confirmed that untreated cattle are "naturally resistant" and also showed that resistance was not abrogated by cure of the naturally-acquired infections. Thus, fecal egg counts after challenge reached mean maxima of 2,432 eggs per gram (epg) in the CC, but only 5 epg and 28 epg in the TC and UC groups, respectively. Similarly, mean worm counts were 85% and 69% lower in the TC and UC groups, respectively, and mean tissue egg densities were reduced by 72-99%, and 56-80%. Histopathologically, the TC and UC groups were also far less affected than the CC. Effective praziquantel treatment does therefore not destroy naturally acquired resistance to S. bovis, and may benefit infected livestock even in the absence of transmission control. The situation in human schistosomiasis is less clear, but there are several epidemiological and experimental indications of a similar conclusion for S. mansoni.

Animals↗