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Biomedical subjects

A A Lebedev

Publications and source records attributed to A A Lebedev.

At least 55 records · Page 3Linked to original sources
PubMed1987

[Diagnostic and prognostic role of organ-specific plasma enzymes in the acute period of cerebral circulatory disorders].

Sixty-two patients with ischemic stroke were studied over time (1st-12th day) for the activity of enzymes and isoenzymes of energy metabolism (CPK, LDH, SDH). It has been shown that the brain-specific CPK BB-isoenzyme may serve as a marker of the severity and extension of brain damage while the aerobic LDH fractions may be useful in evaluation of the reversibility of hypoxic changes in the brain. The authors consider the employment of the studied enzymes for the prognosis of vascular and tissue damage.

Acute Disease↗
PubMed1983

[Characteristics of the latent states of short-term verbal memory in patients with sequelae of cerebral circulatory disorders].

A study of 50 patients in the recovery period of cerebral circulation impairment and 11 healthy subjects was carried out to investigate latent conditions of short-term verbal memory (STVM), using phonooscillography with subsequent statistical computerized treatment. On the basis of the time-course of latent conditions (16500 phonooscillograms), the temporal organization of STVM was studied. It was established that the patients as compared with the healthy subjects showed substantial changes in temporal parameters of mnemonic processes: the duration of latent conditions of STVM increased, the rate of its adaptation decreased, regular pattern and balance of the main temporal parameters were disrupted.

Adaptation, Psychological↗
PubMed1983

[Treatment of wire-induced osteomyelitis].

The author presents data on the incidence and symptoms of "wire" osteomyelitis (11,6%) in 206 patients treated by extrafocal methods of osteosynthesis. The "tunneling" of the wire canal in the bone was used for the surgical treatment of such osteomyelitis. Good results of the treatment allow the method to be recommended for clinical practice.

Adult↗
PubMed1982

[Diagnosis and treatment of the chronic abdominal ischemia syndrome].

This is a collected report on 95 patients with chronic lesions of one or several visceral branches of the abdominal aorta. Restorative operations were performed on 92 patients. Necessity of examining patients with suspicion of the syndrome of chronic abdominal ischaemia in a special vascular surgery department is mandatory. For final diagnosis and choice of surgical tactics aortography in two projections is necessary. The progressive character of the disease is underlined. Restorative operations on the visceral branches of the abdominal aorta are preferred.

Abdomen↗
PubMed1981

[Restoration of the blood flow in the inferior mesenteric artery in reconstructive operations on the aortofemoral segment].

The early postoperative period in 82 patients subjected to operations on the aorta to repair blood-flow along the inferior mesenterial artery was found to have more favourable course. In 78 patients (95.1%) with the repaired blood-flow in the inferior mesenterial artery there were no cases of severe enteroparesis. The authors recommend to repair the blood flow along the inferior mesenterial artery in reconstructive operations on the aorta-femoral segment.

Aorta, Abdominal↗
PubMed1978

[Anti-ischemic action of diuretics].

Rat experiments were conducted for comparative study of the effect of diuretics, injected into the organism in a single dose prior to two-and-a-half-hour ischemia of an only kidney and after it, on the extent of the kidney affection and survival of the animals. It was established that furosemid, etacryn acid and mannitol exert a preventive protective effect in ischemia of the kidneys and considerably increase the survival of rats as compared to the control-group. Analysis of the renal function in the first five days of the postischemic period testifies to the property of the above-mentioned diuretics for normalizing excretory processes on the 2nd-4th days of the action of the injuring agent, and for relieving or shortening the oligoanuric phase of acute renal failure. The significance of metabolic shifts, intratubular hydrodynamics and vascular microcirculation in the mechanism of the protective effect of diuretics in ischemia of the kidneys is discussed.

Animals↗
PubMed1978

[Kidney function and mitochondrial metabolism in excluded renal blood flow against a background of diuretic action].

Single administration of furosemid, etacrine acid and mannitol prior to switching off circulation in the only kidney for 2.5 hrs preserves the renal tissue from ischemic lesion, aids to normalizing the excretory processes on the 2nd--4th days of postischemic period, reduces duration of the oligo--anuric phase in acute renal insufficiency, and raises survival rate in the rats. The above substances are ineffective if administered after cessation of the ischemic period. Etacrin acid and novurit suppress functional activity of isolated mitochondria incubated in hypoxia at 37 degrees. Furosemid and mannitol in these conditions exert no effect. Preliminary administration of furosemid aids to preservation of lumen in proximal tubules of superficial nephrones both during cessation of the renal circulation and in the postischemic period.

Animals↗