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Biomedical subjects

A A Lawson

Publications and source records attributed to A A Lawson.

7 recordsLinked to original sources

Effect of a coronary care unit on mortality from acute myocardial infarction.

The mortality from acute myocardial infarction was compared for 2 years before the introduction of a coronary care unit (C.C.U.), and three and a half years after. The difference was not significant statistically (18% before, and 15% after). There was no reduction in the incidence of cardiac arrest in the C.C.U. period, but resuscitation from cardiac arrest was more successful. The results are considered in the light of previous studies, and the current status of coronary care in district general hospitals is discussed.

Adult

Clonidine in hypertension: a 6-year review.

A study of the use of clonidine in the treatment of patients with hypertension, both in hospital and in the community, during a period of 6 years is reported. Seventy-eight patients (42 males and 36 females) with hypertension were studied during this period both in terms of their immediate response to introduction of clonidine and also the effect of maintenance treatment for periods varying between 2 and 6 years. During the period of study, the hypertension was well controlled in 51 (65.4%) patients. In the remaining 27 patients, clonidine treatment was stopped for a variety of reasons but, despite this, the drug provided effective treatment for period of up to 4 years. Nineteen patients died in the course of the study, but in all these cases the blood pressure remained under adequate control. The clinical response to treatment and the incidence of side-effects are described.

Adult

Partial lipodystrophy with nephrotic syndrome.

A patient with nephrotic syndrome in association with partial lipodystrophy is reported. The features of partial lipodystrophy are well recognized and the renal lesion is a mesangiocapillary glomerulo-nephritis of a dense deposit type with an associated depression of C3. This type of kidney involvement is becoming increasingly recognized as common in the syndrome of partial lipodystrophy.

Adolescent