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Biomedical subjects

A A Klishov

Publications and source records attributed to A A Klishov.

At least 19 recordsLinked to original sources

[Cell-differon organization of the tissues and the problem of wound healing].

Problems on correlation of processes of normal histogenesis and those of physiological and reparative regeneration are discussed. A special attention is paid to the cellular-differon organization of tissue and its significance for understanding cellular mechanisms and ultrastructural bases in tissue regeneration after lesions and use of biostimulators of various origin. Certain peculiarities have been revealed in changes of intra- and interdifferon interrelations of cells in various tissues at regenerative histogenesis. The biostimulators applied differently change duration and manifestation of its stages, that is they influence the internal structure of the process and the cellular-tissue composition of the regenerate.

Animals↗

[Characteristics of myohistogenesis during experimental mono- and bilocal distraction osteosynthesis].

Regularities of the skeletal muscle tissue histogenesis have been studied in the canine shin at its elongation by 50% of its initial length by means of the mono- and bilocal distractive osteosynthesis after Ilizarov. Using light and electron microscopy, it has been stated that under conditions of monolocal distractive osteosynthesis, when the strain effort acts in the area of the muscle belly, together with elongation dystrophic and necrotic changes, proliferation of the intermuscular connective tissue and atrophy of myons increase. In a half of a year, after cessation of distraction there is no complete restoration of the skeletal muscle tissue structure. Under conditions of bilocal distractive osteosynthesis, when the conditions of the muscle distortion are comparable to those existing during the period of the extremity growth, cellular type of regeneration in the skeletal muscle tissue predominates. Therefore growth of the muscle fibers is longitudinal, like that of their growth in the process of ontogenesis and the structure of the muscle tissue of the extremity elongated is preserved. The results of the experiment performed demonstrate certain prospectiveness of application of the bilocal distractive osteosynthesis method in practical orthopedics.

Animals↗