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Biomedical subjects

A A Ibrahim

Publications and source records attributed to A A Ibrahim.

At least 37 records · Page 2Linked to original sources

Arginine catabolism by Mycoplasma meleagridis and its role in pathogenesis.

A thin-layer chromatography technique was used to study the arginine metabolism of Mycoplasma meleagridis. The technique reflected the enzyme activity of the dihydrolase pathway through detection of readily visible end products on X-ray film. Strains of M. meleagridis differing in their pathogenicity for turkeys did not vary in arginine metabolism. In addition, no significant difference was observed in plasma arginine concentrations between M. meleagridis-infected and uninfected poults. It was concluded that the pathogenesis of M. meleagridis infection in turkeys was not based on its competition with the host for arginine.

Animals↗

Hypglycaemia in paediatric anaesthesia: The influence of metoclopramide and oral maltose in paediatric surgical patients.

A safe and effective way to prevent the development of hypoglycaemia in young children during general anaesthesia is to give drinks sweetened with maltose 2 hours before operation. Metoclopramide (Maxolon) is injected intramuscularly to hasten absorption. The postoperative blood sugar in the maltose-treated group (28 patients) was 100+/-22-21 mg/ml (5-5+/-1-232 mmol/litre) and significantly higher ( P less than 0-0005) than in the starved group (22 patients).

Anesthesia, General↗

Mesenteric supernumerary ovary.

Following is a report and a review of literature concerning the supernumerary ovary. Up to now only 7 cases have been reported, and our case appears to be the eighth. The anatomic situation in this case was unusual since it was found in the mesentery. Of the cases previously reported, 2 have been associated with benign cystic teratoma.

Adult↗

Bacteriophage typing of Salmonella. I. Isolation and host range study of bacteriophages.

A series of bacteriophages, lytic for bacteria belonging to the genera Escherichia and Salmonella, were isolated. The phages were isolated from fecal samples, intestinal contents of turkey poults, and carrier cultures of S. typhimurium, S. typhimurium var copenhagen, S. heidelberg, and E. coli. The feasibility of using different habitats as sources of Salmonella phages was evaluated. The carrier cultures were the most promising source for phages active on the serotypes for which the phages were sought. A host range study of the isolated phages was made. Eight phages were selected to develop a phage typing scheme for S. typhimurium, S. typhimurium var copenhagen, and S. heidelberg.

Animals↗

Induction of chromosomal aberrations and sister chromatid exchange in vivo and in vitro by the insecticide cypermethrin.

The induction of chromosomal aberrations and sister chromatid exchange in vivo in mouse spleen and bone marrow as well as in vitro in cultured mouse spleen cells by the insecticide 'Cypermethrin' (cis-trans 1:1) was investigated. The percentage of chromosomal aberrations in the spleen and in the bone marrow as almost the same and reached its maximum 6 h following i.p. injection. The aberrations induced were chromatid and chromosome gaps, fragments and tetraploidy. The insecticide caused a significant and dose-dependent increase in the frequency of sister chromatid exchanges (SCEs) in mouse bone-marrow cells: it reached 11.12 +/- 0.05 per cell after treatment with Cypermethrin at 300 mg kg-1 body wt. compared with 3.7 +/- 0.14 per cell and 4.4 +/- 0.26 per cell in the solvent and control, respectively. The percentage of viable cells in mouse spleen cell cultures reached 87.4% and 99.9% relative to the control after treatment of the cell cultures with 10(-3) and 10(-7) Cypermethrin, respectively. All the tested concentrations of Cypermethrin (0.25-400 micrograms ml-1) induced a high percentage of metaphases with chromosomal aberrations after 4 h of treatment. The mean frequency of SCEs per cell reached 15.1 +/- 0.05 after treatment with Cypermethrin at 4.00 micrograms ml-1 compared with 8.6 +/- 0.23 and 5.9 +/- 0.39 in the solvent and control, respectively. The results indicate that Cypermethrin is genotoxic in mouse spleen and bone marrow as well as in cultured mouse spleen cells.

Animals↗

Human blood groups in Dakahlya, Egypt.

New data on blood groups among Egyptians (Dakahlya province) are obtained by studying eight blood group systems: ABO, Rhesus, MNSs, Kell, Duffy, Kidd, P and Lewis. Comparing our results with the data reported in neighbouring countries, we found in Egypt a high frequency of B, NS, cDe and K genes, a moderately high frequency of P and the presence of Fy gene. The Egyptian population appears as a mixture of African, Asiatic and Arabian characteristics.

Blood Group Antigens↗

Genetic studies in azoospermic patients with the Klinefelter pattern of testicular biopsy.

82 male patients presenting functional azoospermia and klinefelter pattern of testicular biopsy were subjected to genetic, histopathologic, anthropometric and clinical studies. With finer methods of analysis, heterogeneity, within a disorder previously thought to represent one entity is usually revealed. Results of the present investigation suggest that sex chromatin counts cannot substitute chromosomal analysis for the discover of mosaiscism. The study also showed a marked phenotypic overlap between the X-chromatin positive Klinefelter disease and the X-chromatin negative Klinefelter syndrome. This overlap occurs both at the clinical level, documented by anthropometry and histopathologic findings in the testicular biopsy, emphasizing the importance of cytogenetic studies. Cases without the chromosomal aberration in whom we suspect environmental etiology may be described a sphenocopies of the genetic disorder.

Age Factors↗