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Biomedical subjects

A A Filatov

Publications and source records attributed to A A Filatov.

At least 37 records · Page 2Linked to original sources
PubMed1987

[Status of the coronary bed in post-infarction stenocardia].

Selective coronary angiography was performed in 80 patients with early postinfarction angina. All patients showed stenoses in at least one artery. Two vessels were affected in 37.5%, three vessels, in 51.3%, one vessel, in 11.3%. In 8.8% of cases, left coronary-arterial trunk was affected in addition to other arteries. Complete occlusion of one or several arteries was noted in 62.5%. There were marked collaterals in 20% of patients. The only difference between patients who showed relative resistance to medication and those whose condition could be stabilized was in the number of occluded vessels (69.2 and 35.1%, respectively). Coronary arterial lesions were operable in 68% of cases.

Adult↗
PubMed1986

[A method of evaluating the functional state of the thyroid gland].

A simple and reliable method for the assessment of thyroid function was proposed. Data on a high specificity of the radioactive iodine absorption intensity coefficient to differentiate euthyroid and hyperthyroid patients were obtained. The appropriateness of its use in restricted indications for radioimmunoassays was substantiated. The results obtained by the authors were based on the examination of 453 patients.

Humans↗
PubMed1984

[Nuclear mutants of Saccharomyces cerevisiae K2 yeasts with decreased killer activity].

Recessive mutations in two chromosomal unlinked genes kir1 and kir2 of Saccharomyces cerevisiae K2 result in weak killer activity or in complete loss of killer capacity. Kir1 is located on chromosome 7 and is linked to ade7 and ski6. The kir1 and kir2 mutants reveal no alteration of cell membrane. They normally excrete acid phosphatase and have a normal level of mating and sporulation. The analysis of the plasmid nucleic acid in two strains containing the mutant alleles kir1-12 and kir2-23 shows the increased content of L double-stranded DNA, the content of M double-stranded RNA being increased.

Antibiosis↗
PubMed1984

[Comprehensive radiodiagnosis of toxic ademomas of the thyroid].

The results of a comprehensive radionuclide, ultrasound and thermographic study of 18 patients with toxic thyroid adenoma are presented. It has been shown that during thermographic examination temperature difference over the node and the symmetrical region is insignificant and does not exceed 1 degree C in most of the patients. It equally pertains to the comparison of temperatures over the node and the hottest and coldest points in the cervical region. Ultrasound examination makes it possible to determine the shape, size, exact location of the node and its internal structure but gives no opportunity to judge its functional activity. It has been shown that a node in toxic adenoma may have homogeneous as well as heterogeneous echo-structure , elevated or lowered echo-density; changes of degenerative-dystrophic nature are not infrequent.

Adenoma↗
PubMed1984

[Thermographic study of the thyroid gland].

The authors present the results of a thermographic study of the thyroid in patients with diffuse and nodular forms of the goiter. The thermograms and the thermometry data were analysed in 47 patients with diffuse forms of the goiter and in 105 patients with single "cold" and "hot" nodes in the thyroid. Thermography was shown to be a simple harmless method that makes it possible to study the heat production of the thyroid in different pathological processes, e.g. in "cold" nodes delta t over the node was on an average higher by 1 degree C as compared to the symmetrical zone, in "hot" nodes this difference was insignificant, and in diffuse forms of the goiter an isothermal picture was observed. The authors are of opinion that in diffuse forms of the goiter thermography should be considered appropriate as a test for dynamic observation in the process of drug therapy. In "cold" nodes, thermography may serve as a rough test for the choice of patients with suspected thyroid tumors. In "hot" nodes, thermography, according to the authors, is though irrelevant.

Goiter↗
PubMed1981

["Killer" plasmid mutants obtained by exposure to 5-fluorouracil].

Weak killers were tolerated from a killer strain of type k2 of Saccharomyces cerevisiae by treatment with 5-fluorouracil. They segregated sensitive clones during vegetative growth with a frequency from 2 to 20 per cent (nonstable killers, Knst mutants). Alteration of killer activity in these mutants is the result of a mutation in the cytoplasmic killer determinant (KIL-k). The mutant form of this determinant, KIL-nst, partially suppresses the wild type determinant. K-nst have the same dsRNA composition as the wild type killer strain. In some mutants the decrease in M dsRNA amount is possible. The segregation of sensitive mitotic clones of these mutants is probably connected with secondary alterations of the KIL-nst determinant.

Fluorouracil↗