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Biomedical subjects

A A Birkun

Publications and source records attributed to A A Birkun.

30 records · Page 2Linked to original sources
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[Surface-active properties of pulmonary surfactant and the functional activity of type II alveolocytes at various times of the day under experimental conditions].

Complex examination of lungs in 24 healthy guinea pigs in different periods of day using physicochemical, biochemical and electron-microscopic methods has revealed that the highest surface activity of the pulmonary surfactant (PS) is observed in the evening and at night, as phospholipids contain the highest amount of a surfactant of the phosphatidylcholine fraction the most active in the surface-active respect. An increase in the content of PS phospholipids in this period of the day appears to be a consequence of synthesis and secretion intensification in the second-type alveolocytes, that may be due to an increased effect of the vagus nerve.

Animals↗
PubMedDate not supplied

[Pulmonary surfactant in guinea pigs after toxic exposure to CCl4].

The surface-active properties of lung surfactant were studied in 32 guinea pigs given CCl4 according to a schedule. The surface activity of the surfactant is inhibited in the experimental animals under the effect of hepatotrophic poison (CCl4) due to the disturbed metabolism of its phospholipids, which is a consequence of the diminished lipid-synthesizing function of the liver. Diminution of the surface-active properties of the lung surfactant and disturbance of its qualitative composition may be regarded as the cause of the development of extensive atelectases in the animals' lungs.

Animals↗
PubMedDate not supplied

[Viruses of whales and dolphins].

DNA- and RNA-genome viruses of whales and dolphins belong to families Poxviridae, Herpesviridae, Adenoviridae, Orthomyxoviridae, Paramyxoviridae, Togaviridae, Picornaviridae. Virological, serological and pathomorphological signs of infection have been registered in Odontoceti (bottle-nosed dolphin, Atlantic white-sided dolphin, striped dolphin, harbona porpoise, white-beaked dolphin, common dolphin, sperm whale, pilot whale, white whale) and Musticeti (sei whale, fin whale, gray whale, and bowheaded whale). A brief characteristic of diseases is presented. No relations of some viruses with pathologic states of Cetacea were found.

Animals↗
PubMedDate not supplied

[Microphytic algae in the pathology of the cetaceans].

The review includes the analysis of the world literature (1913-1995) about the problems of interrelations, between microorganisms (microphytic algae and cyanobacteria) and marine mammals (whales and dolphins). Special attention is payed to the parasitological, bioindicative and toxicological aspects of microalgae inhabiting the surface of the skin integuments and respiratory organs of cetaceans, as well as their environment. There is the list of the algal species overgrowing the animals bodies and their hosts. The most of the epibionts are belonging to diatoms, there are also some cyanobacteria and green algae. The probability of the influence of the algological factor on the hosts health and a possibility of the microalgae use to evaluate the status of animals and their environment have been discussed.

Animal Diseases↗