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Biomedical subjects

A A Adamian

Publications and source records attributed to A A Adamian.

At least 19 recordsLinked to original sources

[Reconstructive surgeries after extensive resections of anterior abdominal and chest walls for tumors].

Experience of reconstructive surgeries after extensive resections of anterior abdominal and chest walls performed on account of tumors is described. Recovery of integrity of anterior abdominal wall was performed by serial grafting with dura mater and polypropylene net implant. The thorax was repaired with special grafts of the ribs and sternum. The integrity of the skin was reestablished with either suturing of the separated flaps or transposition of myodermal flap on vascular pedicle.

Abdominal Wall↗

[Development of new biologically active dressings and methodology of their use].

Results of development of new biologically active dressings and up-to-date methodology of local treatment of wounds (based on their differential application according to phase and features of wound process) are demonstrated. Data about main properties and specific activity of new biologically active dressings based on natural and synthetic polymers with immobilized drugs are presented. Future trends and efficacy of their appliance in complex treatment of purulent and necrotic wounds are demonstrated.

Acrylates↗

[One-stage formation of urinary bladder, restoration of symphysis with correction of congenital defects of external and internal genital organs].

One-stage combined surgery in a female patient with total extrophy of the urinary bladder after uretherosigmostomy was performed for the first time with participation of surgeons, gynecologists and urologists. Corrective surgeries in these patients must be performed for the purpose of creation of isolated urinary reservoir for prophylaxis of pyelonephritis and chronic renal insufficiency. Correction of symphysis defect was carried out with polypropylene endograft. This surgery was performed to provide quality of life and reproductive function of the patient.

Adult↗

[Management of large and giant postoperative ventral hernias].

The experience of the Department for Plastic Surgery of the A.V. Vishnevsky. Institute of Surgery of RAMS in surgical treatment of 262 patients with postoperative hernias of the anterior abdominal wall has been summarized for the period from 1993 to 1998. 138 patients (test group) had large and giant hernias, 124 (control group)--small and middle-sized postoperative hernias. In large and giant hernias more frequently (46.1%) combined plastic reconstruction of the anterior abdominal wall was used rather than in small and middle-sized hernias (21.5%). In the majority of patients in control group (78.5%) autoplasty of the abdominal wall defect was carried out. In the long term period relapses developed in 9 (7.0%) patients of the test group. In 7 cases the relapse developed after the autoplasty (10.1%), and in 2 cases--after the use of combined method (3.4%). This supports perspectiveness of the method of postoperative hernioplasty by the combined method. Lethality rate after hernioplasty in the test group made up 2.3% (3 patients).

Adult↗

[The classification and surgical correction of postlactation involution of the breasts].

On the basis of investigations performed a classification is made systematizing postlactational involution according to different parameters and degree. It facilitates objectivization of indications to different correcting operative interventions on mammary glands with postlactational involution and choice of the optimum complex of surgical measures for correction of the mammary gland. It allows prognosis of its contour and esthetic results.

Adult↗

[Neurologic disorders in patients with Madelung's lipomatosis].

The authors had 21 patients with a rare disease, Madelung's lipomatosis. Vegetative disorders of segmental and suprasegmental levels were revealed in all patients. The character of neuropathies in Madelung's lipomatosis is discussed in detail. According to the authors, it is a complex syndrome with peripheral, vegetative, and vascular disorders. The accompanying secondary scalenus syndrome produces a peculiar clinical picture of neuropathy. The existence of neurological disorders dictates the need for complex (surgical and medicamentous) treatment of patients with Madelung's lipomatosis.

Adult↗

[Clinical significance of the determination of protein C dependent disorders of hemostasis in surgical patients].

Diagnostic value of protein C measurements was investigated in 159 surgical patients with diseases of the liver, great vessels, and wound infection. Protein C antigen was detected by ELISA with specific antibodies to protein C. The changes of protein C antigenic activity correlated with severity of hepatic disorders. Inhibition of protein C synthetic activity went on in parallel with a fall in pseudocholine esterase concentrations. This suggests feasibility of protein C measurements for examination of protein production by the liver. Characteristics and location of the lesions in great vessels were also related to protein C antigen levels. The fall in this antigen quantity was observed in patients with purulent wound infection. The greater the fall, the more serious the patient's condition became.

Blood Coagulation Disorders↗

[A choice of reconstructive plastic surgery with endoprosthesis of the breast after radical mastectomy].

The creation of silicone endoprosthesis led to new approaches in solving the problems of plastic replacement of the breast after radical mastectomy. Two variants of reconstructive plastic operations with endoprosthetics of the breast were employed: group one--the formation of the seat of the endoprosthesis using a transposed musculocutaneous flap from the latissimus dorsi muscle; group two--the formation of the seat of the endoprosthesis by stretching the skin with a specially designed stretcher-expander and subsequent implantation of the endoprosthesis. The first method is rather injurious, sometimes cannot be performed because of anatomical contraindications, and is fraught with the development of necroses in the transposed tissues. Among 34 patients operated on by the first method two had marginal necrosis of the skin above the endoprosthesis. No complications were recorded among the 46 patients who underwent operation by the second method. The condition of the endoprosthesis and the tissues surrounding it was appraised in the immediate and late periods by radiological and ultrasonic examination. The variants of endoprosthetics of the breast which we applied may be employed with competence in clinical practice, but a reconstructive-plastic operation with the use of a skin expander is preferable.

Adult↗

[Classification and terminological designation of Madelung's lipomatosis].

From experience in the treatment of 18 patients with Madelung's lipomatosis the authors suggest a system of designation of the spread of the disease embracing the possible localizations of the tumor. The system of recording the spread and marked character of the adipose tumors makes it possible to appraise the developmental stage of the disease. It is suggested that 4 stages of the disease are distinguished. According to the type of growth, two forms of tumors are distinguished: nodular and diffuse. Systemic designation and the form of the tumor give a more complete idea of the disease and thus allow the optimal tactics of surgery to be chosen. Among the numerous terms suggested for the disease, the most appropriate, reflecting the essence of the disease is "Madelung's lipomatosis". The authors suggest it for unification of the designations of the disease and easier literature search and generalization of information on this rare disease.

Humans↗